Cajun Chicken and Shrimp Alfredo
This Cajun Chicken and Shrimp Alfredo recipe is a delightful blend of flavors that brings together tender chicken, succulent shrimp, and a creamy Cajun parmesan sauce. Perfect for any occasion—be it a family dinner or a special gathering—this dish is sure to impress. What sets it apart is the rich blend of spices that elevate the classic Alfredo, making it both comforting and exciting.

Why You’ll Love This Recipe
- Quick and Easy: This dish can be prepared in just 40 minutes, making it ideal for weeknight dinners.
- Flavorful Sauce: The creamy Cajun parmesan sauce packs a punch with every bite, offering a taste sensation you won’t forget.
- Versatile Ingredients: Enjoy this meal with fettuccine or switch things up with your favorite pasta type.
- Crowd Pleaser: With its combination of chicken and shrimp, this recipe caters to various palates and is perfect for family gatherings.
- One-Pan Wonder: Minimal cleanup required since everything cooks in one skillet!
Tools and Preparation
Before diving into the cooking process, ensure you have the right tools at hand. These will make your cooking experience smooth and enjoyable.
Essential Tools and Equipment
- Deep skillet
- Pot for boiling pasta
- Measuring cups and spoons
- Knife and cutting board
- Mixing spoon
Importance of Each Tool
- Deep skillet: Allows for even cooking of chicken and shrimp while providing enough space for the sauce.
- Pot for boiling pasta: Ensures your fettuccine cooks evenly to the perfect al dente texture.
Ingredients
For the Pasta
- 8 ounces uncooked fettuccine
For the Protein
- 2 chicken breasts (cut into 1 pieces)
- 1/2 pound shrimp (I used 31/40 size) (thawed & peeled)
For Seasoning
- 1/2 teaspoon garlic powder
- 1/2 tablespoon + 1/2 tablespoon Cajun seasoning (use a low or no salt variety)
For the Sauce
- 2 tablespoons olive oil
- 2 tablespoons butter
- 1 cup heavy/whipping cream
- 4 ounces cream cheese (I used 1/2 block of Philly)
- 2 cloves garlic (minced)
- 1 cup freshly grated parmesan cheese
- Salt & pepper (to taste)
How to Make Cajun Chicken and Shrimp Alfredo
Step 1: Prepare Cream Cheese
Take the cream cheese out of the fridge 30+ minutes prior to starting the recipe or microwave it for 20-30 seconds to soften.
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Step 2: Cook Fettuccine
Boil a salted pot of water for the pasta. Cook it al dente according to package directions.
Step 3: Thaw Shrimp
If using frozen shrimp, thaw them under cool running water. Peel them (leave tails on if desired), then pat dry. Cut chicken into 1 pieces. Sprinkle both shrimp and chicken with garlic powder and 1/2 tablespoon of Cajun seasoning.
Step 4: Cook Shrimp
Add olive oil to a deep skillet over medium-high heat. Once hot, cook shrimp for about 3 minutes, flipping once. Transfer cooked shrimp to a plate.
Step 5: Cook Chicken
In the same skillet, add chicken pieces. Cook for 5-6 minutes or until cooked through, stirring occasionally for browning. Transfer cooked chicken to the same plate as shrimp.
Step 6: Make Sauce
Remove skillet from heat. Add butter, heavy cream, cream cheese, remaining Cajun seasoning, and minced garlic. Return to stove on medium heat; stir until cream cheese dissolves into sauce.
Step 7: Thicken Sauce
Allow sauce to bubble gently for about 2-3 minutes or until slightly thickened.
Step 8: Combine Ingredients
Stir in grated parmesan cheese. Add cooked shrimp and chicken back into the pan. Warm through for a couple of minutes and season with additional salt & pepper as needed.
Step 9: Final Touches
(Optional) Add a splash of hot pasta water (a tablespoon or two) before draining fettuccine to thin out the sauce slightly. Toss drained pasta with sauce immediately before serving. Top with extra grated parmesan, chopped parsley, or a squeeze of lemon for added flavor!
How to Serve Cajun Chicken and Shrimp Alfredo
Cajun Chicken and Shrimp Alfredo is a delicious dish that can be served in various ways to enhance its flavor and presentation. Here are some fun serving suggestions to elevate your dining experience.
Garnish with Fresh Herbs
- Chopped parsley: A sprinkle of fresh parsley adds color and a hint of freshness to the rich sauce.
- Basil leaves: Fresh basil provides a sweet, aromatic touch that pairs well with the creamy Alfredo.
Add a Zesty Twist
- Lemon wedges: Serving lemon wedges on the side allows guests to add a splash of citrus for brightness.
- Hot sauce: Offer a selection of hot sauces for those who enjoy an extra kick of heat alongside their meal.
Pair with Fresh Bread
- Garlic bread: Crispy garlic bread is perfect for soaking up the creamy sauce and complements the flavors beautifully.
- Crusty baguette: A sliced baguette can be served warm, providing a delightful contrast to the creamy pasta.
Create a Salad Side
- Caesar salad: The crisp romaine and tangy dressing create a refreshing balance to the rich pasta.
- Mixed greens: A simple salad with vinaigrette offers lightness and enhances the overall meal experience.

How to Perfect Cajun Chicken and Shrimp Alfredo
To achieve the best Cajun Chicken and Shrimp Alfredo, follow these tips for an unforgettable dish.
- Use fresh ingredients: Choose fresh chicken, shrimp, and herbs for maximum flavor.
- Control the heat: Adjust the amount of Cajun seasoning based on your spice preference; you can always add more later.
- Cook pasta al dente: This ensures the pasta holds its shape and texture when mixed with the sauce.
- Stir continuously: When adding cheese to the sauce, stir constantly to avoid lumps and achieve a smooth consistency.
Best Side Dishes for Cajun Chicken and Shrimp Alfredo
To complement your Cajun Chicken and Shrimp Alfredo, consider these side dishes that enhance your meal’s overall appeal.
- Garlic Bread: Perfect for dipping into the creamy sauce, garlic bread adds crunch and flavor.
- Caesar Salad: This classic salad provides crisp greens with zesty dressing, balancing out the richness of the pasta.
- Roasted Vegetables: Seasonal vegetables roasted until tender bring vibrant colors and nutritious elements to your plate.
- Steamed Asparagus: Lightly steamed asparagus offers a fresh bite that pairs well with creamy dishes like Alfredo.
- Coleslaw: A tangy coleslaw adds crunch and acidity, cutting through the richness of the dish beautifully.
- Grilled Corn on the Cob: Sweet corn complements spicy flavors perfectly while giving a fun summer vibe to your dinner table.
Common Mistakes to Avoid
Making Cajun Chicken and Shrimp Alfredo can be a delightful experience, but there are common mistakes that can affect the dish’s outcome.
- Overcooking the Pasta: Cooking the fettuccine too long can make it mushy. Always follow package instructions for al dente pasta.
- Using Cold Cream Cheese: If not softened, cold cream cheese won’t blend well into the sauce. Ensure it’s at room temperature or microwave it briefly.
- Skipping the Seasoning: Neglecting to season your chicken and shrimp can lead to blandness. Be generous with Cajun seasoning to enhance flavors.
- Not Thawing Shrimp Properly: Improperly thawed shrimp can release excess water, making the dish watery. Thaw in cool water and pat dry before cooking.
- Rushing the Sauce: A rushed sauce might not thicken properly. Allow it to bubble gently so flavors develop and reach the right consistency.

Storage & Reheating Instructions
Refrigerator Storage
- Store leftovers in an airtight container.
- Refrigerate for up to 3 days.
Freezing Cajun Chicken and Shrimp Alfredo
- Use freezer-safe containers for storage.
- Freeze for up to 2 months for best quality.
Reheating Cajun Chicken and Shrimp Alfredo
- Oven: Preheat to 350°F (175°C). Place in an oven-safe dish, cover with foil, and heat for 15-20 minutes.
- Microwave: Heat in short intervals (1-2 minutes), stirring between each until warmed through.
- Stovetop: Warm over low heat, adding a splash of cream or pasta water if needed to loosen the sauce.
Frequently Asked Questions
What is Cajun Chicken and Shrimp Alfredo?
Cajun Chicken and Shrimp Alfredo is a creamy pasta dish featuring tender chicken and shrimp seasoned with zesty Cajun spices, served over fettuccine.
Can I use different types of pasta?
Yes! While fettuccine works great, feel free to substitute with penne or linguine based on your preference.
How spicy is Cajun Chicken and Shrimp Alfredo?
The spice level depends on the Cajun seasoning used. Opt for mild varieties if you prefer a less spicy dish.
Can I customize this recipe?
Absolutely! You can add vegetables like bell peppers or broccoli for extra flavor and nutrients.
Final Thoughts
Cajun Chicken and Shrimp Alfredo combines rich flavors with creamy goodness, making it a perfect meal for any occasion. Its versatility allows you to customize it easily with different vegetables or proteins. Give this recipe a try, and enjoy a comforting dish that’s sure to impress!
Cajun Chicken and Shrimp Alfredo
- Total Time: 40 minutes
- Yield: Serves 4
Description
Cajun Chicken and Shrimp Alfredo is a tantalizing pasta dish that marries the richness of creamy parmesan sauce with the bold flavors of Cajun spices. Featuring tender chicken and succulent shrimp, this dish is perfect for any occasion—from family dinners to special gatherings.
Ingredients
- 8 ounces uncooked fettuccine
- 2 chicken breasts (cut into 1-inch pieces)
- ½ pound shrimp (31/40 size, thawed & peeled)
- 1 cup heavy cream
- 4 ounces cream cheese
- 1 cup freshly grated parmesan cheese
- 2 tablespoons olive oil
- Garlic powder
- Cajun seasoning
Instructions
- Soften cream cheese before starting.
- Boil salted water and cook fettuccine until al dente.
- Thaw shrimp under cool water, peel, and pat dry; season chicken and shrimp with garlic powder and Cajun seasoning.
- In a deep skillet, heat olive oil over medium-high heat; cook shrimp for about 3 minutes, then remove.
- Add chicken to the skillet, cooking until browned (5-6 minutes); transfer to the plate with shrimp.
- Make the sauce: stir butter, heavy cream, cream cheese, garlic, and remaining Cajun seasoning in the skillet until smooth.
- Thicken sauce for 2-3 minutes; add parmesan cheese, then return chicken and shrimp to heat through.
- Toss cooked fettuccine with sauce; serve warm.
- Prep Time: 10 minutes
- Cook Time: 30 minutes
- Category: Main
- Method: Skillet
- Cuisine: Cajun
Nutrition
- Serving Size: 1 plate (approximately 350g)
- Calories: 620
- Sugar: 4g
- Sodium: 850mg
- Fat: 36g
- Saturated Fat: 18g
- Unsaturated Fat: 14g
- Trans Fat: 0g
- Carbohydrates: 56g
- Fiber: 2g
- Protein: 32g
- Cholesterol: 175mg






